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A few years ago a paper was published, Effect of ancient population structure on the degree of polymorphism shared between modern human populations and ancient hominins, in PNAS, which argued that ancient population structure within Africa might be the reason that non-African populations are genetically closer to Neandertals. The basic logic is simple. If within... 阅读更多
By now you may have heard that mitochondrial DNA, passed down the female lineage, has been extracted from a ~XNUMX year old human fossil from Spain. If you haven't heard, I recommend Ewen Callaway and Carl Zimmer's takes. The paper is at Nature, so gated, A mitochondrial genome sequence of a hominin from Sima de... 阅读更多
With all the crazy talk about George Church and an adventurous young woman conspiring to bring back Neandertals, I do think it is important to keep in mind that we can bring back an individual with a predominantly Neandertal genome in a very old fashioned manner: controlled breeding. The most humane and viable manner in... 阅读更多
Birds of a Feather: Neanderthal Exploitation of Raptors and Corvids: The hypothesis that Neanderthals exploited birds for the use of their feathers or claws as personal ornaments in symbolic behaviour is revolutionary as it assigns unprecedented cognitive abilities to these hominins. This inference, however, is based on modest faunal samples and thus may not represent... 阅读更多
Neandertal ancestry "Iced":
Yesterday I pointed out that David Reich had a moderately dismissive attitude toward the new paper in PNAS, Effect of ancient population structure on the degree of polymorphism shared between modern human populations and ancient hominins. Here's what Reich said: Here's what Nick Patterson, Reich's colleague told me via email: Ancient structure in Africa was... 阅读更多
Dienekes tips me off to the fact that the long-awaited Reich lab paper on Neandertal admixture dating has finally been put on arXiv! The date of interbreeding between Neandertals and modern humans: This isn't the only group working on the Neandertal genomic admixture story. From reading his blog you probably know that John Hawks is... 阅读更多
An interview with paleoanthropologist Chris Stringer:   I do find it curious that Chris used the term "creatures." This probably not intentional, or with serious conscious intent, but Neadertals and Denisovans are creatures I think the ethical issues are strongly mitigated. After all, chimpanzees are used in medical experiments. I assume that the woolly mammoth... 阅读更多
XNUMXandMe finally unveiled a Neanderthal Ancestry estimation feature. I'm at ~XNUMX percent. What I'm curious about is the fact that out of the XNUMX "friends and family" who are surveyed, only two are at XNUMX percent. One of my them is my sibling who I found seems to have the Neandertal copy of a dystrophin... 阅读更多
A few people have pointed me to the recent paper in Science, Tenfold Population Increase in Western Europe at the Neandertal–to–Modern Human Transition. The basic result is obvious, and not totally revolutionary: anatomically modern humans may simply have demographically absorbed the Neandertals (the word "absorbed" has many connotations here obviously). The results are clear in... 阅读更多
So asks a commenter below in relation to the question above. First, why would one even presume that they were red-haired, see my XNUMX post, or the paper in Science: A Melanocortin XNUMX Receptor Allele Suggests Varying Pigmentation Among Neanderthals. In humans loss of pigmentation can usually be thought of as loss of function on... 阅读更多
Image credit:ICHTO Recently something popped up into my Google news feed in regards to "Neanderthal-human mating." If you are a regular reader you know that I'm wild for this particular combination of the "wild thing." But a quick perusal of the press release told me that this was a paper I had already reviewed when... 阅读更多
John Hawks, Europe and China have different Neandertal genes: Guesses? I'm assuming it has something to do with adaptation.
Last week I reported that it turns out that one of my siblings carry a possible Neandertal haplotype on the dystrophin gene. To review, it seems likely that ~XNUMX% of the average non-African's genome is derived from Neandertal populations. But by and large this ancestral quantum seems broadly dispersed through the genome of individuals, so... 阅读更多
After XNUMX's world-shaking revolutions in our understanding of modern human origins, the admixture of Eurasian hominins with neo-Africans, I assumed there was going to be a revisionist look at results which seemed to point to mixing between different human lineages over the past decade. Dienekes links to a case in point, a new paper in... 阅读更多
Neandertals famously had larger cranial capacities than modern humans, and, have gone through multiple phases of de- and re-humanization. A few weeks ago there was a revision of the idea that Neandertals in France ~XNUMX years ago adopted some aspects of modern human culture through diffusion. This was a support for the Neandertal "ooga-booga" thesis.... 阅读更多
I assume by now that everyone has read A Draft Sequence of the Neandertal Genome. It's free to all, so you should. At least look at the figures. Also, if you haven't at least skimmed the supplement, you should do that as well. It's nearly XNUMX pages, and basically feels more like a collection of... 阅读更多
在科学中,安·吉本斯 (Ann Gibbons) 有一篇很长的报道,史前接触史。 它非常值得一读,但在付费墙后面。 如果您没有访问权限,我想重点介绍一个特定部分:杂交的发现驳斥了一个长期存在的模型的最狭窄形式,该模型预测所有生物...... 阅读更多
Here's the UCSC Genome Browser page for the Neandertal genome. Ensembl is supposed to have something up soon, but I don't see it. Here's the Anfo Short Read Aligner/Mapper; you can download it on that page. Page XNUMX of the online supplement has some configuration file code on it which might be useful. Also, make... 阅读更多
I'm still digesting the papers on the Neandertals which just came out. You can find them here. If you have questions, please read the papers first. They're open access, so free to all. There's a lot to mull over, and I don't know what I can add right now, but I will note: XNUMX) There's... 阅读更多
We're all a bit of a Neanderthal: I will have a thorough write-up when I get a hold of the paper, which should be soon. As I said, this is a story of genomics, not just genetics. XNUMX-XNUMX% is not trivial. The Daily Telegraph has more: They were surprised to find that Neanderthals were more... 阅读更多
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